Filipin complex

CAS No. 11078-21-0

Filipin complex ( —— )

Catalog No. M23112 CAS No. 11078-21-0

Filipin, produced as a mixture of related compounds known as the filipin complex (filipins I-IV) in nature.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 78 In Stock
25MG 157 In Stock
50MG 225 In Stock
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Biological Information

  • Product Name
    Filipin complex
  • Note
    Research use only, not for human use.
  • Brief Description
    Filipin, produced as a mixture of related compounds known as the filipin complex (filipins I-IV) in nature.
  • Description
    Filipin, produced as a mixture of related compounds known as the filipin complex (filipins I-IV) in nature, is a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure. Filipin III is the major component of Filipin.
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Fungal
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    11078-21-0
  • Formula Weight
    654.8
  • Molecular Formula
    C??H??O?? (for Filipin III)
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 100 mg/mL (152.72 mM);Ethanol : 10 mg/mL (15.27 mM; ultrasonic and warming and heat to 60°C)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kelly PM, et al. Separation of the filipin complex by gradient-elution high performance liquid chromatography. J Antibiot (Tokyo). 1985 Apr;38(4):485-9. 2. Payero TD, et al. Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivatives. Microb Cell Fact. 2015 Aug 7;14:114.
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